Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management
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چکیده
منابع مشابه
Heterogeneity in Fanconi anemia: evidence for 2 new genetic subtypes.
Fanconi anemia (FA) is an autosomal recessive syndrome featuring diverse symptoms including progressive bone marrow failure and early occurrence of acute myeloid leukemia. Nine genetic subtypes have been described for FA (A, B, C, D1, D2, E, F, G, and L), all of which have been connected to distinct disease genes, except B. Here we report on 8 unrelated FA patients who were excluded from the kn...
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Background & Aims: In recent years the issues surrounding competency-based education (CBE) increased attention and debate among health professionals and the international conferences and pilot projects proposed by a growing number of many of the issues of education magazines Medical critically examined. Because it had not been provided in nursing competency-based framework, providing a comprehe...
متن کاملSubtyping of Fanconi anemia patients: implications for clinical management.
Fanconi anemia (FA) is a rare autosomal recessive disease characterized by progressive bone marrow failure, congenital anomalies, and predisposition to cancer. At least 8 complementation groups for FA are known (A, B, C, D1, D2, E, F, G), and 7 FA genes have been cloned. FA cells are highly sensitive to the DNA crosslinking agents, mitomycin C (MMC) or diepoxybutane (DEB), thus providing the ba...
متن کاملMolecular pathogenesis and clinical management of Fanconi anemia.
Fanconi anemia (FA) is a rare genetic disorder associated with a high frequency of hematological abnormalities and congenital anomalies. Based on multilateral efforts from basic scientists and clinicians, significant advances in our knowledge of FA have been made in recent years. Here we review the clinical features, the diagnostic criteria, and the current and future therapies of FA and descri...
متن کاملa fundamental study of "histiriographic metafiction", and "literary genres", as introduced in "new historical philosophy", and tracing them in the works of julian barnes.
abstract a fundamental study of “historio-graphic metafiction” and “literary genres”, as introduced in “new historical philosophy”, and tracing them in the works of julian barnes having studied the two novels, the porcupine and arthur & george, by julian barnes, the researcher has applied linda hutcheon’s historio-graphic metafictional theories to them. the thesis is divided into five cha...
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ژورنال
عنوان ژورنال: Redox Biology
سال: 2021
ISSN: 2213-2317
DOI: 10.1016/j.redox.2021.101860